GSE206528

Human Corpus Cavernosum Atlas

This atlas profiles human corpus cavernosum with normal erectile function and organic erectile dysfunction. It captures fibroblast, smooth muscle, endothelial, pericyte, Schwann…

GEO accession
GSE206528
Species
Homo sapiens
Tissue
Corpus cavernosum
Assay
Single-cell RNA-seq
Cells
64,740
Samples
8
Genes
33,694
Cell metadata fields
4

UMAP preview

Click to enlarge
Figure legend：The UMAP preview is colored by cell annotations. Open the visualization page for full interaction and filtering.

Dataset Description

This atlas profiles human corpus cavernosum with normal erectile function and organic erectile dysfunction. It captures fibroblast, smooth muscle, endothelial, pericyte, Schwann and immune populations, supporting exploration of tissue heterogeneity and intercellular signaling.

Eight tissue samples: three with normal erectile function, three non-diabetic ED and two diabetic ED. Normal-function tissue was collected at tumor resection margins.

Annotation notes

The two annotation levels are not a strict hierarchy. Original labels are retained; cell_type is the default.

Associated Publication

[1]

Zhao L, Han S, Su H, Li J, Zhi E, Li P, et al. Single-cell transcriptome atlas of the human corpus cavernosum. Nat Commun. 2022;13(1):4302. doi: 10.1038/s41467-022-31950-9. PMID: 35879305.

PubMed ↗ · DOI ↗

Data SourceGSE206528

NCBI GEO GSE206528

View GEO record ↗

Data Preview

Five deterministically sampled cells are shown for a quick structural check.

Row Cell ID UMAP 1 UMAP 2 Cell group
1 AAACCCAAGAGGGTGG-1_1_1 -6.697 3.079 CC EC
2 GTGCAGCGTCTCGGGT-1_3_1 -8.202 0.977 CC EC
3 TCTATACAGTGAGTGC-1_5_1 2.916 2.210 APOC1+ FB
4 CCTGTTGGTAACAGTA-1_1 -9.326 2.283 CC EC
5 TTTGTTGTCCGATAAC-1_2 5.579 -3.978 CC SMC