GSE149512

Human Germ Cell Lineage Atlas

This germ cell subset of the human testis developmental atlas describes transcriptional states from spermatogonia through spermatocytes to spermatids. It shares the GSE149512…

GEO accession
GSE149512
Species
Homo sapiens
Tissue
Testis
Assay
Single-cell RNA-seq
Cells
22,777
Samples
10
Genes
59,976
Cell metadata fields
3

Atlas schematic preview

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Figure legend：Schematic of tissue and cell populations.

Dataset Description

This germ cell subset of the human testis developmental atlas describes transcriptional states from spermatogonia through spermatocytes to spermatids. It shares the GSE149512 source cohort with the developmental atlas and is not an independent donor cohort.

Fourteen detailed populations and four broader annotations from the normal human developmental cohort; this is not an independent cohort.

Annotation notes

LZ009: 5 years old; LZ005: 8 years old.

Associated Publication

[1]

Zhao L, Yao C, Xing X, Jing T, Li P, Zhu Z, et al. Single-cell analysis of developing and azoospermia human testicles reveals central role of Sertoli cells. Nat Commun. 2020;11(1):5683. doi: 10.1038/s41467-020-19414-4. PMID: 33173058.

PubMed ↗ · DOI ↗

Data SourceGSE149512

NCBI GEO GSE149512

View GEO record ↗

Data Preview

Five deterministically sampled cells are shown for a quick structural check.

Row Cell ID UMAP 1 UMAP 2 Cell group
1 AACCGCGAGCGACGTA_1 6.296 4.595 SSC1
2 CTACATTCAGCCCACA_3 -0.913 6.691 Z.SPC
3 566947_7 -10.104 -2.871 SPC7
4 CCTACCAGTTCGAATC_1 4.819 -7.508 SPT3
5 465813_9 5.825 -0.955 SPT4