GSE168545

Rat Corpus Cavernosum Atlas

This atlas compares young and aged rat corpus cavernosum from GSE168545. It includes fibroblast, proliferating fibroblast, smooth muscle, endothelial, adipocyte and immune…

GEO accession
GSE168545
Species
Rattus norvegicus
Tissue
Corpus cavernosum
Assay
Single-cell RNA-seq
Cells
7,134
Samples
—
Genes
22,050
Cell metadata fields
12

Atlas schematic preview

Click to enlarge
Figure legend：Schematic of tissue and cell populations.

Dataset Description

This atlas compares young and aged rat corpus cavernosum from GSE168545. It includes fibroblast, proliferating fibroblast, smooth muscle, endothelial, adipocyte and immune annotations. The source study investigated cellular heterogeneity and age-associated erectile dysfunction, with a focus on fibroblasts.

The delivered atlas is a 7,134-cell subset with Young and Old groups. The source study used five young and five old rats; donor identifiers are not retained in this object.

Associated Publication

[1]

Liu Q, Song Y, Cui Y, Hu C, Luo Y, Hu D, et al. Heterogeneity of fibroblasts is a hallmark of age-associated erectile dysfunction. Int J Biochem Cell Biol. 2023;156:106343. doi: 10.1016/j.biocel.2022.106343. PMID: 36503049.

PubMed ↗ · DOI ↗

Data SourceGSE168545

NCBI GEO GSE168545

View GEO record ↗

Data Preview

Five deterministically sampled cells are shown for a quick structural check.

Row Cell ID UMAP 1 UMAP 2 Cell group
1 ATCGCCTTCTAGTCAG-2 2.627 -3.418 FB
2 GCGGATCCAATGGCCC-2 -4.007 -1.178 FB
3 CTACGGGTCAAGCCTA-1 -2.589 4.047 VSMC
4 GAGACTTGTTACGATC-1 0.215 1.404 CCSMC
5 TACGCTCAGACGCAGT-1 1.943 5.532 FB.pro