GSE182786

Human Testis Aging Atlas

This atlas compares young and older human testes in GSE182786 and retains BMI-associated subgroups among older donors. The source study examined cell-type-specific aging patterns…

GEO accession
GSE182786
Species
Homo sapiens
Tissue
Testis
Assay
Single-cell RNA-seq
Cells
42,035
Samples
12
Genes
36,601
Cell metadata fields
5

UMAP preview

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Dataset Description

This atlas compares young and older human testes in GSE182786 and retains BMI-associated subgroups among older donors. The source study examined cell-type-specific aging patterns and their association with elevated body mass index.

Four young, five LowBMI_Old and three HighBMI_Old donors, with 12,427, 18,928 and 10,680 cells respectively.

Associated Publication

[1]

Nie X, Munyoki SK, Sukhwani M, Schmid N, Missel A, Emery BR, et al. Single-cell analysis of human testis aging and correlation with elevated body mass index. Dev Cell. 2022;57(9):1160-1176.e5. doi: 10.1016/j.devcel.2022.04.004. PMID: 35504286.

PubMed ↗ · DOI ↗

Data SourceGSE182786

NCBI GEO GSE182786

View GEO record ↗

Data Preview

Five deterministically sampled cells are shown for a quick structural check.

Row Cell ID UMAP 1 UMAP 2 Cell group
1 Young1.AAACCCAGTCATCCCT.1 -10.735 -3.492 SPC7
2 Young4.GCCATGGCAGTTAAAG.1 -6.164 -14.286 SSC2
3 Older4.GATCAGTAGCCGGAAT.1 -9.198 4.079 SPT2
4 Older6.GATCAGTAGCATGATA.1 -6.659 5.714 SPT2
5 Older8.TTTGTTGGTATGGAAT.1 11.713 9.807 VSM